Detecting IOP Fluctuations in Glaucoma Patients

Detecting IOP Fluctuations in Glaucoma Patients

Lowering intraocular pressure (IOP) remains the guiding principle of glaucoma management. Although IOP is the only treatable risk factor, its 24-hour behavior is poorly understood. Current glaucoma management usually relies on single IOP measurements during clinic hours, even though IOP is a dynamic parameter with rhythms dependent on individual patients. It has further been shown that most gla...

Selective laser trabeculoplasty reduces mean IOP and IOP variation in normal tension glaucoma patients

PURPOSE To evaluate the effect of selective laser trabeculoplasty (SLT) in normal tension glaucoma (NTG) patients. PATIENTS AND METHODS A retrospective review was performed of NTG patients who had undergone SLT at the Duke University Eye Center between 12/2002 and 7/2005. For each eye of each patient at pre-laser and post-laser time points, the IOP measurements were summarized by mean, standa...

The Role of IOP in Glaucoma

Retinal vessel reaction to short-term IOP elevation in ocular hypertensive and glaucoma patients.

PURPOSE Regulation of ocular blood flow might be impaired in glaucoma patients. We compared the reaction of retinal vessels to a short-term increase of intraocular pressure (IOP), using a retinal vessel analyzer (RVA), in normal volunteers, ocular hypertensive patients (OH) and primary open angle glaucoma patients (POAG). METHODS Ten healthy subjects (56+/-8 years, IOP 13.7+/-1.6 mmHg), 10 OH...

Detecting temperature fluctuations at equilibrium.

The Gibbs and the Boltzmann definition of temperature agree only in the macroscopic limit. The ambiguity in identifying the equilibrium temperature of a finite-sized 'small' system exchanging energy with a bath is usually understood as a limitation of conventional statistical mechanics. We interpret this ambiguity as resulting from a stochastically fluctuating temperature coupled with the phase...